Controlled synthesis of highly-branched plasmonic gold nanoparticles through peptoid engineering Yan, Feng, Liu, Lili, Walsh, Tiffany R., Gong, Yu, El-Khoury, Patrick Z., Zhang, Yanyan, Zhu, Zihua, De Yoreo, James J., Engelhard, Mark H., Zhang, Xin and Chen, Chun-Long 2018, Controlled synthesis of highly-branched plasmonic gold nanoparticles through peptoid engineering, Nature communications, vol. 9, no. 1, doi: 10.1038/s41467-018-04789-2. Attached Files Name Description MIMEType Size Downloads walsh-controlledsynthesis-2018.pdf Published version application/pdf 3.43MB 115 Title Controlled synthesis of highly-branched plasmonic gold nanoparticles through peptoid engineering Author(s) Yan, Feng Liu, Lili Walsh, Tiffany R. orcid.org/0000-0002-0233-9484 Gong, Yu El-Khoury, Patrick Z. Zhang, Yanyan Zhu, Zihua De Yoreo, James J. Engelhard, Mark H. Zhang, Xin Chen, Chun-Long Journal name Nature communications Volume number 9 Issue number 1 Article ID 2327 Total pages 8 Publisher Nature Publishing Group Place of publication London, Eng. Publication date 2018-06-13 ISSN 2041-1723 2041-1723 Keyword(s) Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics BINDING PEPTIDE NANOMATERIAL SYNTHESIS BIOMIMETIC POLYMERS INORGANIC MATERIALS SEQUENCE GROWTH PROTEINS DESIGN RECOGNITION SURFACES Summary In nature, specific biomolecules interacting with mineral precursors are responsible for the precise production of nanostructured inorganic materials that exhibit complex morphologies and superior performance. Despite advances in developing biomimetic approaches, the design rules for creating sequence-defined molecules that lead to the synthesis of inorganic nanomaterials with predictable complex morphologies are unknown. Herein we report the design of sequence-defined peptoids for controlled synthesis of highly branched plasmonic gold particles. By engineering peptoid sequences and investigating the resulting particle formation mechanisms, we develop a rule of thumb for designing peptoids that predictively enabled the morphological evolution from spherical to coral-shaped nanoparticles. Through a combination of hyperspectral UV-Vis extinction microscopy and three-photon photoemission electron microscopy, we demonstrate that the individual coral-shaped gold nanoparticles exhibit a plasmonic enhancement as high as 105-fold. This research significantly advances our ultimate vision of predictive bio-inspired materials synthesis using sequence-defined synthetic molecules that mimic proteins and peptides. Language eng DOI 10.1038/s41467-018-04789-2 Field of Research MD Multidisciplinary HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2018, The Authors Free to Read? Yes Use Rights Persistent URL http://hdl.handle.net/10536/DRO/DU:30111158 Document type: Journal Article Collections: Institute for Frontier Materials Open Access Collection GTP Research Related Links Link Description Connect to Elements publication management system Go to link with your DU access privileges   Connect to published version (open access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Thu, 12 Jul 2018, 16:02:47 EST Fri, 13 Jul 2018, 05:05:11 EST Fri, 13 Jul 2018, 08:11:38 EST Mon, 30 Jul 2018, 15:56:06 EST Tue, 07 Aug 2018, 15:50:34 EST Tue, 07 Aug 2018, 15:53:17 EST Tue, 07 Aug 2018, 15:55:19 EST Thu, 09 Aug 2018, 11:37:49 EST Fri, 07 Sep 2018, 19:10:31 EST Filtered Full Citation counts:   Cited 51 times in TR Web of Science Cited 52 times in Scopus Search Google Scholar Access Statistics: 411 Abstract Views, 115 File Downloads  -  Detailed Statistics Created: Thu, 12 Jul 2018, 16:02:47 EST