Weight change and cardiometabolic outcomes in postpartum women with history of gestational diabetes Lim, Siew, Versace, Vincent L, O'Reilly, Sharleen, Janus, Edward and Dunbar, James 2019, Weight change and cardiometabolic outcomes in postpartum women with history of gestational diabetes, Nutrients, vol. 11, no. 4, pp. 1-13, doi: 10.3390/nu11040922. Attached Files Name Description MIMEType Size Downloads Title Weight change and cardiometabolic outcomes in postpartum women with history of gestational diabetes Author(s) Lim, Siew orcid.org/0000-0002-5333-6451 Versace, Vincent L orcid.org/0000-0002-8514-1763 O'Reilly, Sharleen orcid.org/0000-0003-3547-6634 Janus, Edward Dunbar, James orcid.org/0000-0003-0866-4365 Journal name Nutrients Volume number 11 Issue number 4 Article ID 922 Start page 1 End page 13 Total pages 13 Publisher MDPI Place of publication Basel, Switzerland Publication date 2019-04 ISSN 2072-6643 2072-6643 Keyword(s) diabetes prevention program gestational diabetes postpartum weight gain weight loss Science & Technology Life Sciences & Biomedicine Nutrition & Dietetics Summary Weight gain after childbirth is a significant risk factor for type 2 diabetes (T2DM) development after gestational diabetes mellitus (GDM). The level of weight loss achieved in diabetes prevention programs for women after GDM is often low but its effects on the cardiometabolic risk are not known. In a secondary analysis of a diabetes prevention program in postpartum women with history of gestational diabetes, we evaluated the effect of weight change on the cardiometabolic outcomes at 1-year follow-up. Of the 284 women randomized to the intervention arm, 206 with the final outcome measurements were included in the analyses. Participants were categorized into weight loss (>2 kg, n = 74), weight stable (±2 kg, n = 74) or weight gain (>2 kg, n = 58) groups. The weight loss group had significantly greater decrease in glycated hemoglobin (HbA1c) than the weight gain group (-0.1 + 0.4% vs. 0 + 0.4%, p = 0.049). The weight loss group had significantly greater decrease in total cholesterol and low-density lipoprotein cholesterol cholesterol than the other two groups (p < 0.05). The weight gain group had significantly greater increase in triglyceride and triglyceride:high-density lipoprotein cholesterol ratio compare with the other groups (p < 0.01). Overall, a small amount of weight loss and prevention of further weight gain was beneficial to the cardiometabolic outcomes of postpartum women after GDM. Language eng DOI 10.3390/nu11040922 Field of Research 1111 Nutrition and Dietetics HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2019, the authors Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30121206 Document type: Journal Article Collections: Faculty of Health PVC's Office - Health Open Access Collection Related Links Link Description Link to full-text (open access)   Connect to published version Go to link with your DU access privileges   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Wed, 01 May 2019, 22:10:40 EST Thu, 02 May 2019, 05:01:19 EST Sat, 01 Jun 2019, 02:32:59 EST Wed, 05 Jun 2019, 15:52:08 EST Thu, 06 Jun 2019, 06:04:22 EST Sat, 15 Jun 2019, 02:30:32 EST Thu, 27 Jun 2019, 11:19:50 EST Thu, 27 Jun 2019, 11:21:18 EST Thu, 27 Jun 2019, 11:22:27 EST Fri, 15 Nov 2019, 07:37:32 EST Filtered Full Citation counts:   Cited 1 times in TR Web of Science Cited 3 times in Scopus Search Google Scholar Access Statistics: 367 Abstract Views, 2 File Downloads  -  Detailed Statistics Created: Wed, 05 Jun 2019, 15:52:08 EST