Novel antibacterial nanofibers of chitosan and polyurethane prepared by electrospinning

Kang, Wei Min, Cheng, Bo Wen, Li, Quanxiang and Zuo, Fang Fang 2011, Novel antibacterial nanofibers of chitosan and polyurethane prepared by electrospinning, Advanced Materials Research, vol. 150-151, pp. 1452-1456, doi: 10.4028/

Title Novel antibacterial nanofibers of chitosan and polyurethane prepared by electrospinning
Author(s) Kang, Wei Min
Cheng, Bo Wen
Li, QuanxiangORCID iD for Li, Quanxiang
Zuo, Fang Fang
Journal name Advanced Materials Research
Volume number 150-151
Start page 1452
End page 1456
Total pages 5
Publisher Trans Tech Publications, Ltd.
Publication date 2011-01-03
ISSN 1022-6680
Summary The chitosan(CS)/polyurethane(PU) blend nanofibers have been prepared for the first time by electrospinning. Formic acid (FA) and Hexafluoroisopropanol (HFIP) were found to be the co-solvent for electrospinning. The CS/PU blend solutions in various ratios were studied for electrospinning into nanofibers. The diameter and morphology of the fibers were shown by scanning electron microscope (SEM). It was found that the average diameter of the chitosan/PU blend fibers became larger, and the morphology of the fibers became finer with the content of PU increasing. To show the molecular interactions, CS/PU fibers were characterized by Fourier transform infrared spectroscopy (FT-IR). Moreover, the antibaterial activity of blend nanofibers against Escherichia coil (E.coil) was measured via optical density method. The blend nanofibers exhibited satisfying antibacterial activity against E.coil, even the chitosan concentration was only 5wt%. Therefore, the spun nanofibers are expected to be used in the native extracellular matrix for tissue engineering.
Language eng
DOI 10.4028/
Indigenous content off
Field of Research 09 Engineering
HERDC Research category C1.1 Refereed article in a scholarly journal
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Document type: Journal Article
Collections: Institute for Frontier Materials
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