The role of body composition in diverticular disease

Freckelton, Julia, Holt, Darcy, Borsaru, Adina, Gwini, Stella May, Croagh, Daniel and Moore, Gregory 2018, The role of body composition in diverticular disease, International journal of colorectal disease, vol. 33, no. 9, pp. 1299-1302, doi: 10.1007/s00384-018-3058-y.

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Title The role of body composition in diverticular disease
Author(s) Freckelton, Julia
Holt, Darcy
Borsaru, Adina
Gwini, Stella MayORCID iD for Gwini, Stella May
Croagh, Daniel
Moore, Gregory
Journal name International journal of colorectal disease
Volume number 33
Issue number 9
Start page 1299
End page 1302
Total pages 4
Publisher Springer
Place of publication Cham, Switzerland
Publication date 2018-09
ISSN 0179-1958
Keyword(s) Diverticulosis
Extramyocellular fat
Visceral fat
Body composition
Summary Background: Diverticular disease is a common, chronic inflammatory disease of the bowel. This study investigates the differences in body composition between patients with diverticular disease and those without. Methods: Appropriate patients were identified using a search of the radiology database. Demographic and disease information was gathered using scanned medical records. Body composition analysis was performed at level L3 using single-slice computed tomography techniques. Results: Two hundred seventy-one patients were included in this study: 83 controls, 93 with diverticulosis and 95 with diverticulitis. Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area (VFA), than the control group (p < 0.001, p < 0.001). Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area to subcutaneous fat area ratio (VFA:SCFA), than the control group (p = 0.005, p = 0.019). Only diverticulosis was associated with increased levels of extramyocellular fat, when compared to the control group (p = 0.001). Conclusion: Diverticular disease is associated with a higher amount and a higher proportion of visceral fat than seen in controls without diverticular disease.
Language eng
DOI 10.1007/s00384-018-3058-y
Indigenous content off
Field of Research 1103 Clinical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
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Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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