Current film coating designs for colon-targeted oral delivery

Tran, Ha Lien Phuong and Tran, Thao T.D. 2020, Current film coating designs for colon-targeted oral delivery, Current Medicinal Chemistry, doi: 10.2174/0929867327666200604170048.


Title Current film coating designs for colon-targeted oral delivery
Author(s) Tran, Ha Lien PhuongORCID iD for Tran, Ha Lien Phuong orcid.org/0000-0001-8463-7516
Tran, Thao T.D.
Journal name Current Medicinal Chemistry
Publisher Bentham Science Publishers Ltd.
Place of publication Schiphol, The Netherlands
Publication date 2020-06-04
ISSN 0929-8673
Keyword(s) Colonic delivery
film coating
film modulation
nanoparticle coating
natural-based film
Summary Colon-targeted oral delivery has recently attracted a substantial number of studies on both systemic and localtreatments. Among approaches for colonic delivery, film coatings have been demonstrated as effective elements of the drugdelivery systems because they can integrate multiple release strategies, such as pH-controlled release, time-controlled release and enzyme-triggered release. Moreover, coating layer modulations, natural film materials and nanoparticle coatingshave been vigorously investigated with promising applications. This review aims to describe the primary approaches for improving drug delivery to the colon in the last decade. The outstanding importance of current developments in film coatingswill advance dosage form designs and lead to the development of efficient colon-targeted oral delivery systems.
Notes In Press
Language eng
DOI 10.2174/0929867327666200604170048
Indigenous content off
Field of Research 0304 Medicinal and Biomolecular Chemistry
0601 Biochemistry and Cell Biology
1115 Pharmacology and Pharmaceutical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30139531

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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