Burden of infection in Australian infants

Rowland, Rebecca, Sass, Zia, Ponsonby, Anne-Louise, Pezic, Angela, Tang, Mimi L. K., Vuillermin, Peter, Gray, Lawrence, Burgner, David and Barwon Infant Study Investigator Group 2020, Burden of infection in Australian infants, Journal of Paediatrics and Child Health, vol. 57, no. 2, pp. 204-211, doi: 10.1111/jpc.15174.

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Title Burden of infection in Australian infants
Author(s) Rowland, Rebecca
Sass, Zia
Ponsonby, Anne-Louise
Pezic, Angela
Tang, Mimi L. K.
Vuillermin, PeterORCID iD for Vuillermin, Peter orcid.org/0000-0002-6580-0346
Gray, Lawrence
Burgner, David
Barwon Infant Study Investigator Group
Journal name Journal of Paediatrics and Child Health
Volume number 57
Issue number 2
Start page 204
End page 211
Total pages 8
Publisher Wiley-Blackwell Publishing
Place of publication Chichester, Eng.
Publication date 2020-01-01
ISSN 1034-4810
1440-1754
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Pediatrics
disease burden
gastroenteritis
health resource
incidence
respiratory tract infection
RESPIRATORY-INFECTIONS
RISK-FACTORS
CHILDREN
ADMISSIONS
HYGIENE
BIRTH
Barwon Infant Study Investigator Group
Summary Aim: To determine the incidence, risk factors and health service utilisation for infection in the first 12 months of life in a population-derivedAustralian pre-birth cohort.Methods: The Barwon Infant Study is a population-derived pre-birth cohort with antenatal recruitment (n = 1074) based in Geelong, Victoria,Australia. Infection data were collected by parent report, and general practitioner and hospital records at 1, 3, 6, 9 and 12 months of age. We calculated the incidence of infection, attendance at a health service with infection and used multiple negative binomial regression to investigate theeffects of a range of exposures on incidence of infection.Results: In the first 12 months of life, infections of the upper and lower respiratory tract (henceforth ‘respiratory infections’), conjunctivitis andgastroenteritis occurred at a rate of 0.35, 0.04 and 0.04 episodes per child-month, respectively. A total of 482 (72.4%) infants attended a generalpractitioner with an infection and 69 (10.4%) infants attended the emergency department. Maternal antibiotic exposure in pregnancy and havingolder siblings were associated with respiratory infection. Childcare attendance by 12 months of age was associated with respiratory infectionsand gastroenteritis. Breastfeeding, even if less than 4 weeks in total, was associated with reduced respiratory infection.Conclusion: Infection, especially of the respiratory tract, is a common cause of morbidity in Australian infants. Several potentially modifiablerisk factors were identified, particularly for respiratory infections. Most infections were managed by general practitioners and 1 in 10 infantsattended an emergency department with infection in the first year of life.
Language eng
DOI 10.1111/jpc.15174
Indigenous content off
Field of Research 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
1117 Public Health and Health Services
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2020, Paediatrics and Child Health Division (The Royal Australasian College of Physicians)
Persistent URL http://hdl.handle.net/10536/DRO/DU:30143406

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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