Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?

Morris, Gerwyn, Athan, Eugene, Walder, Ken, Bortolasci, Chiara C., O'Neil, Adrienne, Marx, Wolf, Berk, Michael, Carvalho, André F., Maes, Michael and Puri, Basant K. 2020, Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?, Life sciences, vol. 262, pp. 1-14, doi: 10.1016/j.lfs.2020.118541.

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Title Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?
Author(s) Morris, Gerwyn
Athan, EugeneORCID iD for Athan, Eugene orcid.org/0000-0001-9838-6471
Walder, KenORCID iD for Walder, Ken orcid.org/0000-0002-6758-4763
Bortolasci, Chiara C.ORCID iD for Bortolasci, Chiara C. orcid.org/0000-0002-0794-6363
O'Neil, Adrienne
Marx, WolfORCID iD for Marx, Wolf orcid.org/0000-0002-8556-8230
Berk, MichaelORCID iD for Berk, Michael orcid.org/0000-0002-5554-6946
Carvalho, André F.
Maes, Michael
Puri, Basant K.
Journal name Life sciences
Volume number 262
Article ID 118541
Start page 1
End page 14
Total pages 14
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2020-12
ISSN 0024-3205
1879-0631
Keyword(s) Antiviral treatment
COVID-19
Immunomodulation
Macrolide
SARS-CoV-2
Science & Technology
Life Sciences & Biomedicine
Medicine, Research & Experimental
Pharmacology & Pharmacy
Research & Experimental Medicine
RESPIRATORY SYNDROME CORONAVIRUS
SYSTEMIC-LUPUS-ERYTHEMATOSUS
OBSTRUCTIVE PULMONARY-DISEASE
PRO-INFLAMMATORY CYTOKINES
HIV-INFECTED PATIENTS
ELEVATED GOLGI PH
RHEUMATOID-ARTHRITIS
ENDOPLASMIC-RETICULUM
VIRAL LOAD
KAPPA-B
Language eng
DOI 10.1016/j.lfs.2020.118541
Indigenous content off
Field of Research 110999 Neurosciences not elsewhere classified
0601 Biochemistry and Cell Biology
1115 Pharmacology and Pharmaceutical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30144270

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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