Ultraprocessed food and chronic noncommunicable diseases: A systematic review and meta‐analysis of 43 observational studies Lane, Melissa M., Davis, Jessica A., Beattie, Sally, Gómez‐Donoso, Clara, Loughman, Amy, O'Neil, Adrienne, Jacka, Felice, Berk, Michael, Page, Richard, Marx, Wolfgang and Rocks, Tetyana 2020, Ultraprocessed food and chronic noncommunicable diseases: A systematic review and meta‐analysis of 43 observational studies, Obesity Reviews, vol. Early View, no. Online Version of Record before inclusion in an issue, doi: 10.1111/obr.13146. Attached Files Name Description MIMEType Size Downloads Title Ultraprocessed food and chronic noncommunicable diseases: A systematic review and meta‐analysis of 43 observational studies Author(s) Lane, Melissa M. Davis, Jessica A. Beattie, Sally Gómez‐Donoso, Clara Loughman, Amy orcid.org/0000-0002-0257-1443 O'Neil, Adrienne Jacka, Felice orcid.org/0000-0002-9825-0328 Berk, Michael orcid.org/0000-0002-5554-6946 Page, Richard orcid.org/0000-0002-2225-7144 Marx, Wolfgang orcid.org/0000-0002-8556-8230 Rocks, Tetyana orcid.org/0000-0002-4529-5872 Journal name Obesity Reviews Volume number Early View Issue number Online Version of Record before inclusion in an issue Article ID obr.13146 Total pages 19 Publisher Wiley-Blackwell Publishing Place of publication Chichester, Eng. Publication date 2020-11-09 ISSN 1467-7881 1467-789X Keyword(s) NOVA meta-analysis noncommunicable disease ultraprocessed food Summary This systematic review and meta‐analysis investigated the association between consumption of ultraprocessed food and noncommunicable disease risk, morbidity and mortality. Forty‐three observational studies were included (N = 891,723): 21 cross‐sectional, 19 prospective, two case‐control and one conducted both a prospective and cross‐sectional analysis. Meta‐analysis demonstrated consumption of ultraprocessed food was associated with increased risk of overweight (odds ratio: 1.36; 95% confidence interval [CI], 1.23‐1.51; P < 0.001), obesity (odds ratio: 1.51; 95% CI, 1.34‐1.70; P < 0.001), abdominal obesity (odds ratio: 1.49; 95% CI, 1.34‐1.66; P < 0.0001), all‐cause mortality (hazard ratio: 1.28; 95% CI, 1.11‐1.48; P = 0.001), metabolic syndrome (odds ratio: 1.81; 95% CI, 1.12‐2.93; P = 0.015) and depression in adults (hazard ratio: 1.22; 95% CI, 1.16‐1.28, P < 0.001) as well as wheezing (odds ratio: 1.40; 95% CI, 1.27‐1.55; P < 0.001) but not asthma in adolescents (odds ratio: 1.20; 95% CI, 0.99‐1.46; P = 0.065). In addition, consumption of ultraprocessed food was associated with cardiometabolic diseases, frailty, irritable bowel syndrome, functional dyspepsia and cancer (breast and overall) in adults while also being associated with metabolic syndrome in adolescents and dyslipidaemia in children. Although links between ultraprocessed food consumption and some intermediate risk factors in adults were also highlighted, further studies are required to more clearly define associations in children and adolescents. Language eng DOI 10.1111/obr.13146 Indigenous content off Field of Research 11 Medical and Health Sciences 17 Psychology and Cognitive Sciences HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2020, World Obesity Federation Persistent URL http://hdl.handle.net/10536/DRO/DU:30145337 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Fri, 13 Nov 2020, 07:53:39 EST Fri, 13 Nov 2020, 07:54:15 EST Fri, 13 Nov 2020, 10:31:31 EST Sat, 14 Nov 2020, 04:01:23 EST Wed, 09 Dec 2020, 05:06:38 EST Sat, 12 Dec 2020, 01:42:33 EST Tue, 15 Dec 2020, 14:54:45 EST Tue, 15 Dec 2020, 15:06:57 EST Tue, 15 Dec 2020, 18:31:42 EST Sat, 09 Jan 2021, 01:31:04 EST Filtered Full Citation counts:   Cited 23 times in TR Web of Science Cited 30 times in Scopus Search Google Scholar Access Statistics: 284 Abstract Views, 6 File Downloads  -  Detailed Statistics Created: Fri, 13 Nov 2020, 10:31:31 EST

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