Openly accessible

Learning from scaling up ultra-rapid genomic testing for critically ill children to a national level

Best, Stephanie, Brown, Helen, Lunke, Sebastian, Patel, Chirag, Pinner, Jason, Barnett, Christopher P, Wilson, Meredith, Sandaradura, Sarah A, McClaren, Belinda, Brett, Gemma R, Braithwaite, Jeffrey and Stark, Zornitza 2021, Learning from scaling up ultra-rapid genomic testing for critically ill children to a national level, npj Genomic Medicine, vol. 6, no. 1, pp. 1-9, doi: 10.1038/s41525-020-00168-3.

Attached Files
Name Description MIMEType Size Downloads

Title Learning from scaling up ultra-rapid genomic testing for critically ill children to a national level
Author(s) Best, Stephanie
Brown, HelenORCID iD for Brown, Helen orcid.org/0000-0002-5460-3654
Lunke, Sebastian
Patel, Chirag
Pinner, Jason
Barnett, Christopher P
Wilson, Meredith
Sandaradura, Sarah A
McClaren, Belinda
Brett, Gemma R
Braithwaite, Jeffrey
Stark, Zornitza
Journal name npj Genomic Medicine
Volume number 6
Issue number 1
Article ID 5
Start page 1
End page 9
Total pages 9
Publisher Nature Publishing Group
Place of publication London, Eng.
Publication date 2021
ISSN 2056-7944
2056-7944
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Genetics & Heredity
Summary In scaling up an ultra-rapid genomics program, we used implementation science principles to design and investigate influences on implementation and identify strategies required for sustainable “real-world” services. Interviews with key professionals revealed the importance of networks and relationship building, leadership, culture, and the relative advantage afforded by ultra-rapid genomics in the care of critically ill children. Although clinical geneticists focused on intervention characteristics and the fit with patient-centered care, intensivists emphasized the importance of access to knowledge, in particular from clinical geneticists. The relative advantage of ultra-rapid genomics and trust in consistent and transparent delivery were significant in creating engagement at initial implementation, with appropriate resourcing highlighted as important for longer term sustainability of implementation. Our findings demonstrate where common approaches can be used and, significantly, where there is a need to tailor support by professional role and implementation phase, to maximize the potential of ultra-rapid genomic testing to improve patient care.
Language eng
DOI 10.1038/s41525-020-00168-3
Indigenous content off
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30147903

Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 1 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 32 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Mon, 08 Feb 2021, 07:16:15 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.