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The wonderful activities of the genus Mentha: not only antioxidant properties

Tafrihi, Majid, Imran, Muhammad, Tufail, Tabussam, Gondal, Tanweer Aslam, Caruso, Gianluca, Sharma, Somesh, Sharma, Ruchi, Atanassova, Maria, Atanassov, Lyubomir, Fokou, Patrick Valere Tsouh and Pezzani, Raffaele 2021, The wonderful activities of the genus Mentha: not only antioxidant properties, Molecules, vol. 26, no. 4, pp. 1-22, doi: 10.3390/molecules26041118.

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Title The wonderful activities of the genus Mentha: not only antioxidant properties
Author(s) Tafrihi, Majid
Imran, Muhammad
Tufail, Tabussam
Gondal, Tanweer Aslam
Caruso, Gianluca
Sharma, Somesh
Sharma, Ruchi
Atanassova, Maria
Atanassov, Lyubomir
Fokou, Patrick Valere Tsouh
Pezzani, Raffaele
Journal name Molecules
Volume number 26
Issue number 4
Article ID 1118
Start page 1
End page 22
Total pages 22
Publisher MDPI
Place of publication Basel, Switzerland
Publication date 2021-02
ISSN 1420-3049
1420-3049
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemistry & Molecular Biology
Chemistry, Multidisciplinary
Chemistry
mint
Mentha
phytochemicals
essential oils
anticancer
antimicrobial
Mentha, phytochemicals
Summary Medicinal plants and their derived compounds have drawn the attention of researchers due to their considerable impact on human health. Among medicinal plants, mint (Mentha species) exhibits multiple health beneficial properties, such as prevention from cancer development and anti-obesity, antimicrobial, anti-inflammatory, anti-diabetic, and cardioprotective effects, as a result of its antioxidant potential, combined with low toxicity and high efficacy. Mentha species are widely used in savory dishes, food, beverages, and confectionary products. Phytochemicals derived from mint also showed anticancer activity against different types of human cancers such as cervix, lung, breast and many others. Mint essential oils show a great cytotoxicity potential, by modulating MAPK and PI3k/Akt pathways; they also induce apoptosis, suppress invasion and migration potential of cancer cells lines along with cell cycle arrest, upregulation of Bax and p53 genes, modulation of TNF, IL-6, IFN-γ, IL-8, and induction of senescence phenotype. Essential oils from mint have also been found to exert antibacterial activities against Bacillus subtilis, Streptococcus aureus, Pseudomonas aeruginosa, and many others. The current review highlights the antimicrobial role of mint-derived compounds and essential oils with a special emphasis on anticancer activities, clinical data and adverse effects displayed by such versatile plants.
Language eng
DOI 10.3390/molecules26041118
Indigenous content off
Field of Research 0304 Medicinal and Biomolecular Chemistry
0305 Organic Chemistry
0307 Theoretical and Computational Chemistry
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30149897

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.