Disruption of cytokine signalling in leukemia

Bulleeraz, Vilasha 2019, Disruption of cytokine signalling in leukemia, Ph.D. thesis, School of Medicine, Deakin University.

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Title Disruption of cytokine signalling in leukemia
Author Bulleeraz, Vilasha
Institution Deakin University
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name Ph.D.
Thesis advisor Ward, Alister C.ORCID iD for Ward, Alister C. orcid.org/0000-0001-7945-7975
Liongue, CliffordORCID iD for Liongue, Clifford orcid.org/0000-0002-1646-4905
Date submitted 2019-12-18
Summary Mutation of specific genes within the so-called ‘cytokine signalling pathway’ have been identified in blood cancers, including leukemia. This thesis modelled two of these leukemia-related mutations in zebrafish, providing new understanding of their biological effects and creating platforms for future testing of therapeutic agents to combat this lethal disease.
Language eng
Indigenous content off
Field of Research 110202 Haematology
111203 Cancer Genetics
110704 Cellular Immunology
Socio Economic Objective 920101 Blood Disorders
Description of original 111 p.
Restricted until 2022-12-04
Copyright notice ┬ęThe author
Persistent URL http://hdl.handle.net/10536/DRO/DU:30150009

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