Metformin for Preventing Type 2 Diabetes Mellitus in Women with a Previous Diagnosis of Gestational Diabetes: A Narrative Review

Versace, Vincent, Beks, Hannah, Wesley, Hannah, McNamara, K, Hague, W, Anjana, RM, Mohan, V, Khunti, K and Dunbar, James 2020, Metformin for Preventing Type 2 Diabetes Mellitus in Women with a Previous Diagnosis of Gestational Diabetes: A Narrative Review, Seminars in Reproductive Medicine, vol. 38, no. 6, pp. 366-376, doi: 10.1055/s-0041-1727203.

Attached Files
Name Description MIMEType Size Downloads

Title Metformin for Preventing Type 2 Diabetes Mellitus in Women with a Previous Diagnosis of Gestational Diabetes: A Narrative Review
Author(s) Versace, VincentORCID iD for Versace, Vincent orcid.org/0000-0002-8514-1763
Beks, HannahORCID iD for Beks, Hannah orcid.org/0000-0002-2851-6450
Wesley, Hannah
McNamara, K
Hague, W
Anjana, RM
Mohan, V
Khunti, KORCID iD for Khunti, K orcid.org/0000-0003-0866-4365
Dunbar, James
Journal name Seminars in Reproductive Medicine
Volume number 38
Issue number 6
Start page 366
End page 376
Total pages 11
Publisher Thieme Medical Publishers
Place of publication New York, N.Y.
Publication date 2020-11
ISSN 1526-8004
1526-4564
Keyword(s) gestational diabetes
Life Sciences & Biomedicine
metformin
Obstetrics & Gynecology
preventive medicine
Reproductive Biology
risk factors
Science & Technology
type 2 diabetes mellitus
LIFE-STYLE INTERVENTION
IMPAIRED GLUCOSE-TOLERANCE
POSTPARTUM FOLLOW-UP
CARDIOVASCULAR-DISEASE
RISK-FACTORS
PREVALENCE
HISTORY
IMPACT
PREGNANCY
PHARMACOKINETICS
Summary AbstractWomen with a history of gestational diabetes mellitus (GDM) are at greater risk of developing type 2 diabetes mellitus (T2DM) when compared with women who have not had GDM. To delay or prevent T2DM, guidelines recommend regular screening in the primary care setting and lifestyle interventions that are largely focused on dietary and physical activity modifications. As the postpartum period can be challenging for women, uptake and engagement in screening and lifestyle interventions have been poor. Poor uptake and engagement places women with a history of GDM at heightened risk for future morbidity and development of T2DM. Metformin has been a longstanding and safe treatment for the control of blood glucose in people with T2DM. Research has supported the efficacy of metformin, used as an adjunct to a lifestyle intervention or as a stand-alone treatment, in preventing T2DM in people at high risk of T2DM. Findings from longitudinal studies have demonstrated the potential for metformin to reduce conversion to T2DM when used by women with a previous diagnosis of GDM. This review examines the potential effectiveness of metformin to reduce the incidence of T2DM among women with a previous diagnosis of GDM in the “real-world” setting.
Language eng
DOI 10.1055/s-0041-1727203
Field of Research 111799 Public Health and Health Services not elsewhere classified
1114 Paediatrics and Reproductive Medicine
Socio Economic Objective 920499 Public Health (excl. Specific Population Health) not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30150324

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 0 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 17 Abstract Views, 2 File Downloads  -  Detailed Statistics
Created: Fri, 23 Apr 2021, 11:39:31 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.