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Extracellular Matrix Enzymes and Immune Cell Biology

McMahon, M, Ye, S, Pedrina, J, Dlugolenski, D and Stambas, John 2021, Extracellular Matrix Enzymes and Immune Cell Biology, Frontiers in Molecular Biosciences, vol. 8, pp. 1-9, doi: 10.3389/fmolb.2021.703868.

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Title Extracellular Matrix Enzymes and Immune Cell Biology
Author(s) McMahon, M
Ye, S
Pedrina, J
Dlugolenski, D
Stambas, JohnORCID iD for Stambas, John orcid.org/0000-0002-5690-2551
Journal name Frontiers in Molecular Biosciences
Volume number 8
Article ID 703868
Start page 1
End page 9
Total pages 9
Publisher Frontiers
Place of publication Lausanne, Switzerland
Publication date 2021-08
ISSN 2296-889X
2296-889X
Keyword(s) a disintegrin and metalloproteinases
a disintegrin and metalloproteinases with thombospondin-1 motifs
ACUTE LUNG INJURY
BINDING
Biochemistry & Molecular Biology
extracellular matrix
HEMOPEXIN DOMAIN
HYALURONAN
immunity
INTRACELLULAR MATURATION
IN-VIVO
Life Sciences & Biomedicine
metalloproteinases
Science & Technology
T-CELLS
TISSUE INHIBITOR
VERSICAN
Summary Remodelling of the extracellular matrix (ECM) by ECM metalloproteinases is increasingly being associated with regulation of immune cell function. ECM metalloproteinases, including Matrix Metalloproteinases (MMPs), A Disintegrin and Metalloproteinases (ADAMs) and ADAMs with Thombospondin-1 motifs (ADAMTS) play a vital role in pathogen defence and have been shown to influence migration of immune cells. This review provides a current summary of the role of ECM enzymes in immune cell migration and function and discusses opportunities and limitations for development of diagnostic and therapeutic strategies targeting metalloproteinase expression and activity in the context of infectious disease
Language eng
DOI 10.3389/fmolb.2021.703868
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30156371

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Citation counts: TR Web of Science Citation Count  Cited 2 times in TR Web of Science
Scopus Citation Count Cited 2 times in Scopus Google Scholar Search Google Scholar
Access Statistics: 45 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Fri, 01 Oct 2021, 08:01:40 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.