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Dietary interventions with or without omega-3 supplementation for the management of rheumatoid arthritis: A systematic review

Raad, T, Griffin, A, George, Elena, Larkin, L, Fraser, A, Kennedy, N and Tierney, AC 2021, Dietary interventions with or without omega-3 supplementation for the management of rheumatoid arthritis: A systematic review, Nutrients, vol. 13, no. 10, pp. 1-22, doi: 10.3390/nu13103506.

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Title Dietary interventions with or without omega-3 supplementation for the management of rheumatoid arthritis: A systematic review
Author(s) Raad, T
Griffin, A
George, ElenaORCID iD for George, Elena orcid.org/0000-0002-1385-2371
Larkin, L
Fraser, A
Kennedy, N
Tierney, AC
Journal name Nutrients
Volume number 13
Issue number 10
Article ID 3506
Start page 1
End page 22
Total pages 22
Publisher MDPI
Place of publication Basel, Switzerland
Publication date 2021-10
ISSN 2072-6643
2072-6643
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Nutrition & Dietetics
dietary interventions
rheumatoid arthritis
omega-3 supplements
nutrition
systematic review
MEDITERRANEAN DIET
CONTROLLED-TRIAL
VEGETARIAN DIET
ELEMENTAL DIET
FOOD
CLASSIFICATION
THERAPY
COMORBIDITIES
INFLAMMATION
SYMPTOMS
Summary Rheumatoid Arthritis (RA) is a chronic autoimmune condition characterized by symptoms of inflammation and pain in the joints. RA is estimated to have a worldwide prevalence of 0.5–1%, with a predominance in females. Diet may play an important role in the symptoms of RA; however, little is known about the effects of various diets. The aim of this systematic review is to explore the effect of dietary interventions, with or without omega-3 supplementation for the management of RA. The electronic databases MEDLINE, EMBASE, CINAHL, and the Cochrane Library were systematically searched for clinical trials investigating dietary interventions, with or without omega-3 supplementation to retrieve papers from inception to April 2021. Randomized and non-randomized controlled trials of dietary interventions in adults with RA were eligible for inclusion. Twenty studies with a total of 1063 participants were included. The most frequently reported outcomes were pain, duration of morning stiffness, joint tenderness, grip strength and inflammatory markers. Dietary interventions with an anti-inflammatory basis may be an effective way for adults with RA seeking complementary treatments, potentially leading to improvements in certain parameters. However, there is a need for longer duration studies that are well-designed and sufficiently powered to investigate the influence of diet on RA.
Language eng
DOI 10.3390/nu13103506
Field of Research 0908 Food Sciences
1111 Nutrition and Dietetics
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30156911

Document type: Journal Article
Collection: Faculty of Health
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Created: Wed, 13 Oct 2021, 07:20:04 EST

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