Implementation of a cellulitis management plan in three australian regional health services to address an evidence–practice gap in antibiotic prescribing
Bishop, J, Jones, M, Farquharson, J, Summerhayes, K, Tucker, R, Smith, M, Cowan, R, Friedman, Deb, Schulz, T, Kong, D and Buising, K 2021, Implementation of a cellulitis management plan in three australian regional health services to address an evidence–practice gap in antibiotic prescribing, Antibiotics, vol. 10, no. 11, pp. 1-12, doi: 10.3390/antibiotics10111288.
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Implementation of a cellulitis management plan in three australian regional health services to address an evidence–practice gap in antibiotic prescribing
Despite the availability of evidence-based guidelines, antibiotics for cellulitis remain inappropriately prescribed. This evidence–practice gap is more evident in low-resource settings, such as rural hospitals. This implementation study developed and introduced a cellulitis management plan to improve antibiotic prescribing for cellulitis in three health services in regional Australia. Appropriateness of antibiotic prescribing for cellulitis at Day 1 was the primary outcome measure. Adults with ICD-10-AM codes for lower-limb cellulitis admitted as inpatients of the three health services between May and November 2019 (baseline, n = 165) and March and October 2020 (post-implementation, n = 127) were included in the assessment. The uptake of the cellulitis management plan was 29.1% (37/127). The appropriateness of antibiotic prescribing for cellulitis at Day 1 was similar at baseline (78.7%, 144/183) and in the intention-to-treat post-implementation group (81.8%, 126/154) [95% CI −5.6% to 11.3%, p = 0.50]. Commencement of the cellulitis management plan resulted in a non-statistically significant increase in antibiotic appropriateness at Day 1 compared to when a cellulitis management plan was not commenced (88.1% vs. 79.5%; 95% CI −5.6% to 19.8%; p = 0.20) Evaluation of more real-world strategies to address evidence–practice gaps, such as the appropriateness of antibiotic prescribing for cellulitis, is required
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