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Implementation of a cellulitis management plan in three australian regional health services to address an evidence–practice gap in antibiotic prescribing

Bishop, J, Jones, M, Farquharson, J, Summerhayes, K, Tucker, R, Smith, M, Cowan, R, Friedman, Deb, Schulz, T, Kong, D and Buising, K 2021, Implementation of a cellulitis management plan in three australian regional health services to address an evidence–practice gap in antibiotic prescribing, Antibiotics, vol. 10, no. 11, pp. 1-12, doi: 10.3390/antibiotics10111288.

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Title Implementation of a cellulitis management plan in three australian regional health services to address an evidence–practice gap in antibiotic prescribing
Author(s) Bishop, J
Jones, M
Farquharson, J
Summerhayes, K
Tucker, R
Smith, M
Cowan, R
Friedman, DebORCID iD for Friedman, Deb orcid.org/0000-0003-2049-3087
Schulz, T
Kong, D
Buising, K
Journal name Antibiotics
Volume number 10
Issue number 11
Article ID 1288
Start page 1
End page 12
Total pages 12
Publisher MDPI AG
Place of publication Basel, Switzerland
Publication date 2021
ISSN 2079-6382
2079-6382
Keyword(s) antibiotic
appropriateness
cellulitis
rural
stewardship
Summary Despite the availability of evidence-based guidelines, antibiotics for cellulitis remain inappropriately prescribed. This evidence–practice gap is more evident in low-resource settings, such as rural hospitals. This implementation study developed and introduced a cellulitis management plan to improve antibiotic prescribing for cellulitis in three health services in regional Australia. Appropriateness of antibiotic prescribing for cellulitis at Day 1 was the primary outcome measure. Adults with ICD-10-AM codes for lower-limb cellulitis admitted as inpatients of the three health services between May and November 2019 (baseline, n = 165) and March and October 2020 (post-implementation, n = 127) were included in the assessment. The uptake of the cellulitis management plan was 29.1% (37/127). The appropriateness of antibiotic prescribing for cellulitis at Day 1 was similar at baseline (78.7%, 144/183) and in the intention-to-treat post-implementation group (81.8%, 126/154) [95% CI −5.6% to 11.3%, p = 0.50]. Commencement of the cellulitis management plan resulted in a non-statistically significant increase in antibiotic appropriateness at Day 1 compared to when a cellulitis management plan was not commenced (88.1% vs. 79.5%; 95% CI −5.6% to 19.8%; p = 0.20) Evaluation of more real-world strategies to address evidence–practice gaps, such as the appropriateness of antibiotic prescribing for cellulitis, is required
Language eng
DOI 10.3390/antibiotics10111288
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30158394

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.