Anti-Angiogenic Properties of Ginsenoside Rg3 Nakhjavani, Maryam, Smith, E, Townsend, AR, Price, TJ and Hardingham, JE 2020, Anti-Angiogenic Properties of Ginsenoside Rg3, Molecules, vol. 25, no. 21, pp. 1-18, doi: 10.3390/molecules25214905. Title Anti-Angiogenic Properties of Ginsenoside Rg3 Author(s) Nakhjavani, Maryam Smith, E Townsend, AR Price, TJ Hardingham, JE Journal name Molecules Volume number 25 Issue number 21 Article ID 4905 Start page 1 End page 18 Total pages 18 Publisher MDPI Place of publication Basel, Switzerland Publication date 2020 ISSN 1420-3049 1420-3049 Keyword(s) 20(R)-ginsenoside Rg3 20(S)-ginsenoside Rg3 angiogenesis Biochemistry & Molecular Biology Chemistry Chemistry, Multidisciplinary COLLAGEN-SYNTHESIS ENDOTHELIAL GROWTH-FACTOR epimer ginsenoside Rg3 HEPATOCELLULAR-CARCINOMA INHIBITS ANGIOGENESIS IONIZATION MASS-SPECTROMETRY Life Sciences & Biomedicine NITRIC-OXIDE SYNTHASE PANAX-GINSENG Physical Sciences PROSTATE-CANCER Science & Technology Summary Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3). Rg3 is an intriguing molecule due to its anti-cancer properties. One facet of the anti-cancer properties of Rg3 is the anti-angiogenic action. This review describes the controversies on the effects and effective dose range of Rg3, summarizes the evidence on the efficacy of Rg3 on angiogenesis, and raises the possibility that Rg3 is a prodrug Language eng DOI 10.3390/molecules25214905 Field of Research 0304 Medicinal and Biomolecular Chemistry 0305 Organic Chemistry 0307 Theoretical and Computational Chemistry HERDC Research category C1 Refereed article in a scholarly journal Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30159018 Document type: Journal Article Collections: Faculty of Health School of Medicine Open Access Collection Related Links Link Description Connect to Elements publication management system Go to link with your DU access privileges   Link to full-text (open access)     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Mon, 22 Nov 2021, 09:34:24 EST Mon, 22 Nov 2021, 15:16:47 EST Mon, 22 Nov 2021, 15:23:15 EST Fri, 26 Nov 2021, 15:14:14 EST Sat, 04 Dec 2021, 01:33:05 EST Sat, 04 Dec 2021, 01:48:07 EST Fri, 14 Jan 2022, 14:34:09 EST Fri, 14 Jan 2022, 15:27:21 EST Fri, 14 Jan 2022, 15:32:32 EST Mon, 17 Jan 2022, 13:57:08 EST Mon, 24 Jan 2022, 14:40:28 EST Mon, 24 Jan 2022, 15:23:46 EST Mon, 24 Jan 2022, 15:32:26 EST Filtered Full Citation counts:   Cited 9 times in TR Web of Science Cited 12 times in Scopus Search Google Scholar Access Statistics: 49 Abstract Views  -  Detailed Statistics Created: Mon, 22 Nov 2021, 09:34:24 EST