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Mechanical thrombectomy for emergent large vessel occlusion: an Australian primary stroke centre workflow analysis

Tiu, J, Watson, T and Clissold, Ben 2021, Mechanical thrombectomy for emergent large vessel occlusion: an Australian primary stroke centre workflow analysis, Internal Medicine Journal, vol. 51, no. 6, pp. 905-909, doi: 10.1111/imj.14843.

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Title Mechanical thrombectomy for emergent large vessel occlusion: an Australian primary stroke centre workflow analysis
Author(s) Tiu, J
Watson, T
Clissold, Ben
Journal name Internal Medicine Journal
Volume number 51
Issue number 6
Start page 905
End page 909
Total pages 5
Publisher Royal Australasian College of Physicians
Place of publication Melbourne, Vic.
Publication date 2021
ISSN 1444-0903
1445-5994
Keyword(s) stroke
thrombectomy
treatment workflow
pre-hospital
door-in-door-out
Summary Background: Time to successful reperfusion is a critical prognostic factor for acute ischaemic stroke. Mechanical thrombectomy has become the gold standard treatment for emergent large vessel occlusion stroke. The timely delivery of this highly specialised procedure to patients outside of metropolitan centres presents a dilemma of inequity, with limited workflow data hindering benchmarking and service optimisation. Aims: To analyse key stroke treatment time parameters from a primary stroke centre existing in a regional centre within a hub-and-spoke delivery model in Victoria, Australia. Methods: Retrospective cohort study of patients transferred from a regional primary stroke centre to a metropolitan comprehensive stroke centre for mechanical thrombectomy between July 2016 and December 2018. Time workflow analysis was conducted from symptom onset to primary stroke centre departure. Results: A total of 55 patients was included in this study with an average age of 70.2 years. Median National Institutes of Health Stroke Scale score on admission was 13 (interquartile range (IQR) 7–17). Median pre-hospital time was 68 min (IQR 56–137) and median door-in-door-out time was 120.5 min (IQR 98–150), constituting 36.1% and 63.9% of total median time from symptom onset to primary stroke centre departure (188.5 min) respectively. There were no significant differences across observed cohort characteristics under linear regression analysis. Conclusion: Protracted pre-hospital and primary stroke centre workflow times can delay effective treatment for patients with acute ischaemic stroke in regional areas. A systems-level approach to streamlining processes in these key areas is required to bridge this inequity in best practice care.
DOI 10.1111/imj.14843
Field of Research 1102 Cardiorespiratory Medicine and Haematology
1103 Clinical Sciences
1117 Public Health and Health Services
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30161485

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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