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Metabolic Syndrome, Cognitive Impairment and the Role of Diet: A Narrative Review

Kouvari, M, D’cunha, NM, Travica, Nikolaj, Sergi, D, Zec, M, Marx, Wolf and Naumovski, N 2022, Metabolic Syndrome, Cognitive Impairment and the Role of Diet: A Narrative Review, Nutrients, vol. 14, no. 2, pp. 1-21, doi: 10.3390/nu14020333.

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Title Metabolic Syndrome, Cognitive Impairment and the Role of Diet: A Narrative Review
Author(s) Kouvari, M
D’cunha, NM
Travica, Nikolaj
Sergi, D
Zec, MORCID iD for Zec, M orcid.org/0000-0002-8556-8230
Marx, Wolf
Naumovski, N
Journal name Nutrients
Volume number 14
Issue number 2
Start page 1
End page 21
Total pages 21
Publisher MDPI
Place of publication Basel, Switzerland
Publication date 2022
ISSN 2072-6643
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Nutrition & Dietetics
metabolic syndrome
dementia
cognitive impairment
cognition
nutrition
healthy aging
DOSE-RESPONSE METAANALYSIS
MEDITERRANEAN DIET
ALZHEIMERS-DISEASE
BLOOD-PRESSURE
LATE-LIFE
INSULIN-RESISTANCE
VEGETABLE INTAKE
TEA CONSUMPTION
GUT MICROBIOTA
FATTY-ACIDS
Summary Background: This narrative review presents the association between metabolic syndrome (MetS), along with its components, and cognition-related disorders, as well as the potential reversal role of diet against cognitive impairment by modulating MetS. Methods: An electronic research in Medline (Pubmed) and Scopus was conducted. Results: MetS and cognitive decline share common cardiometabolic pathways as MetS components can trigger cognitive impairment. On the other side, the risk factors for both MetS and cognitive impairment can be reduced by optimizing the nutritional intake. Clinical manifestations such as dyslipidemia, hypertension, diabetes and increased central body adiposity are nutrition-related risk factors present during the prodromal period before cognitive impairment. The Mediterranean dietary pattern stands among the most discussed predominantly plant-based diets in relation to cardiometabolic disorders that may prevent dementia, Alzheimer’s disease and other cognition-related disorders. In addition, accumulating evidence suggests that the consumption of specific dietary food groups as a part of the overall diet can improve cognitive outcomes, maybe due to their involvement in cardiometabolic paths. Conclusions: Early MetS detection may be helpful to prevent or delay cognitive decline. Moreover, this review highlights the importance of healthy nutritional habits to reverse such conditions and the urgency of early lifestyle interventions.
Language eng
DOI 10.3390/nu14020333
Field of Research 0908 Food Sciences
1111 Nutrition and Dietetics
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30161921

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Citation counts: TR Web of Science Citation Count  Cited 1 times in TR Web of Science
Scopus Citation Count Cited 2 times in Scopus Google Scholar Search Google Scholar
Access Statistics: 12 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Mon, 24 Jan 2022, 07:19:47 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.