Trichothecenes in food and feed: Occurrence, impact on human health and their detection and management strategies Mahato, Dipendra Kumar, Pandhi, S, Kamle, M, Gupta, A, Sharma, B, Panda, BK, Srivastava, S, Kumar, M, Selvakumar, R, Pandey, AK, Suthar, P, Arora, S, Kumar, A, Gamlath, Shirani, Bharti, A and Kumar, P 2022, Trichothecenes in food and feed: Occurrence, impact on human health and their detection and management strategies, Toxicon, vol. 208, pp. 62-77, doi: 10.1016/j.toxicon.2022.01.011. Attached Files Name Description MIMEType Size Downloads Title Trichothecenes in food and feed: Occurrence, impact on human health and their detection and management strategies Author(s) Mahato, Dipendra Kumar Pandhi, S Kamle, M Gupta, A Sharma, B Panda, BK Srivastava, S Kumar, M Selvakumar, R Pandey, AK Suthar, P Arora, S Kumar, A orcid.org/0000-0002-2053-2624 Gamlath, Shirani Bharti, A Kumar, P Journal name Toxicon Volume number 208 Start page 62 End page 77 Total pages 16 Publisher Elsevier Place of publication Amsterdam, The Netherlands Publication date 2022 ISSN 0041-0101 1879-3150 Keyword(s) trichothecenes food and feed contamination human health detection and management strategies Summary Trichothecenes (TCNs) are the mycotoxins produced by many fungal species such as Fusarium, Myrothecium, and Stachybotrys and pose a considerable health risk. Based on their characteristic functional moieties, they are divided into four categories: Type A (T-2, HT-2, diacetoxyscirpenol (DAS), harzianum A, neosolaniol (NEO) and trichodermin), Type B (deoxynivalenol (DON), nivalenol (NIV), trichothecin and fusarenon X), Type C (crotocin) and Type D (satratoxin G & H, roridin A and verrucarin A) with types A and B being the most substantial. TCNs cause growth retardation in eukaryotes, suppress seedling growth or regeneration in plants and could be a reason for animal reproductive failure. Due to the increased frequency of occurrence and widespread distribution of TCNs in food and feed, knowledge of their sources of occurrence is essential to strategise their control and management. Hence, this review provides an overview of various types and sources of TCNs, the associated biosynthetic pathways and genes responsible for production in food and feed. Further, various processing and environmental effects on TCNs production, detection techniques and management strategies are also briefly outlined. DOI 10.1016/j.toxicon.2022.01.011 Field of Research 1115 Pharmacology and Pharmaceutical Sciences HERDC Research category C1 Refereed article in a scholarly journal Persistent URL http://hdl.handle.net/10536/DRO/DU:30162294 Document type: Journal Article Collections: Faculty of Health School of Exercise and Nutrition Sciences Related Links Link Description Connect to published version Go to link with your DU access privileges   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 07 Feb 2022, 07:14:54 EST Mon, 07 Feb 2022, 07:25:51 EST Mon, 07 Feb 2022, 07:36:42 EST Sat, 12 Feb 2022, 01:46:10 EST Wed, 16 Feb 2022, 16:09:28 EST Wed, 06 Apr 2022, 15:54:28 EST Wed, 06 Apr 2022, 16:14:47 EST Wed, 06 Apr 2022, 16:53:41 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 1 times in Scopus Search Google Scholar Access Statistics: 14 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Mon, 07 Feb 2022, 07:14:54 EST