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Childhood atopy and mental health: A prospective, longitudinal investigation

Goodwin, RD, Robinson, M, Sly, Peter and Holt, PG 2017, Childhood atopy and mental health: A prospective, longitudinal investigation, Psychological Medicine, vol. 47, no. 2, pp. 317-325, doi: 10.1017/S0033291716001896.

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Title Childhood atopy and mental health: A prospective, longitudinal investigation
Author(s) Goodwin, RD
Robinson, M
Sly, Peter
Holt, PG
Journal name Psychological Medicine
Volume number 47
Issue number 2
Start page 317
End page 325
Total pages 9
Publisher Cambridge University Press
Place of publication Cambridge, Eng.
Publication date 2017-01
ISSN 0033-2917
1469-8978
Keyword(s) 1966 BIRTH COHORT
allergy
anxiety
Atopy
BEHAVIORAL-PROBLEMS
CHILDREN
cohort study
DEPRESSION
DISORDERS
FAMILY ASSESSMENT DEVICE
FOOD ALLERGY
Life Sciences & Biomedicine
mental health
Psychiatry
Psychology
Psychology, Clinical
QUALITY-OF-LIFE
Western Australia
Social Sciences
Science & Technology
RISK
Summary BackgroundPrior studies have suggested a relationship between atopy and mental health, although methodological barriers have limited the generalizability of these findings. The objective of this study was to investigate the relationship between early-life atopy and vulnerability to mental health problems among youth in the community.MethodData were drawn from the Raine Study (N = 2868), a population-based birth cohort study in Western Australia. Logistic regression and generalized estimating equations were used to examine the relationship between atopy at ages 1–5 years [using parent report and objective biological confirmation (sera IgE)], and the range of internalizing and externalizing mental health problems at ages 5–17 years.ResultsAtopy appears to be associated with increased vulnerability to affective and anxiety problems, compared to youth without atopy. These associations remained significant after adjusting for a range of potential confounders. No relationship was evident between atopy and attention deficit hyperactivity disorder or externalizing problems.ConclusionsFindings are the first linking atopy (measured by both parent report and objective verification) with increased vulnerability to affective and anxiety problems. Therefore, replication is required. If replicated, future research aimed at understanding the possible biological and/or social and environmental pathways underlying these links is needed. Such information could shed light on shared pathways that could lead to more effective treatments for both atopy and internalizing mental health problems.
Language eng
DOI 10.1017/S0033291716001896
Field of Research 1109 Neurosciences
1117 Public Health and Health Services
1701 Psychology
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30164926

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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