Trends and risk factors for omission of early thromboprophylaxis in Australian and New Zealand ICUs between 2009 and 2020. Sahle, Berhe, Pilcher, D, Peter, K, McFadyen, JD and Bucknall, Tracey 2022, Trends and risk factors for omission of early thromboprophylaxis in Australian and New Zealand ICUs between 2009 and 2020., Intensive Care Med, doi: 10.1007/s00134-022-06672-7. Attached Files Name Description MIMEType Size Downloads Title Trends and risk factors for omission of early thromboprophylaxis in Australian and New Zealand ICUs between 2009 and 2020. Author(s) Sahle, Berhe Pilcher, D Peter, K McFadyen, JD orcid.org/0000-0001-9089-3583 Bucknall, Tracey Journal name Intensive Care Med Publisher p Place of publication United States Publication date 2022-04-01 ISSN 1432-1238 Keyword(s) Critically ill Intensive care unit Thromboprophylaxis Venous thromboembolism Summary PURPOSE: Venous thromboembolism (VTE) prophylaxis is effective in reducing VTE events; however, it is underutilized in critically ill patients. We examined trends and risk factors for omission of early thromboprophylaxis within the first 24 h after admission in Australian and New Zealand intensive care units (ICUs) between 2009 and 2020. METHODS: Retrospective analysis of data from the Australian New Zealand Intensive Care Society Adult Patient Database. Data were obtained for 1,465,020 adult admissions between 2009 and 2020. Mixed effects logistic regression modeling (accounting for the random effects of the contributing ICUs) was used to identify factors associated with omission of early thromboprophylaxis. RESULTS: A total of 107,486 (7.3%) ICU patients did not receive any form of thromboprophylaxis within the first 24 h after ICU admission without obvious reasons. Omission of early thromboprophylaxis declined from 13.7% in 2009 to 4% in 2020 (by 70.8%) (P < 0.001). Younger patients were more like to miss out on VTE prophylaxis (odds ratios (OR)per 10-year increase 0.94, 95% CI 0.95-0.99). A documented process for monitoring VTE prophylaxis (ORs 0.90, 95% CI 0.87-0.93) and having a medical lead, dedicated for coordinating ICU quality (ORper 0.1 increase in full-time equivalent 0.97, 95% CI 0.93-0.99), are associated with less omission of VTE prophylaxis. CONCLUSION: Omission of thromboprophylaxis within the first 24 h after ICU admission has declined steadily over the past decade. Documented process for monitoring VTE prophylaxis and having a medical lead for coordinating quality of ICU care could be potential targets for sustaining the improvement in VTE prophylaxis use. Language eng DOI 10.1007/s00134-022-06672-7 Indigenous content off Field of Research 1103 Clinical Sciences 1117 Public Health and Health Services Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30166680 Document type: Journal Article Collections: Faculty of Health School of Nursing and Midwifery Open Access Collection Related Links Link Description Link to full-text (open access)   Connect to published version Go to link with your DU access privileges   Author URL Go to link with your DU access privileges   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Tue, 12 Apr 2022, 08:36:05 EST Tue, 12 Apr 2022, 16:15:25 EST Tue, 12 Apr 2022, 16:20:03 EST Thu, 28 Apr 2022, 06:05:12 EST Mon, 02 May 2022, 08:55:10 EST Mon, 02 May 2022, 14:06:31 EST Thu, 05 May 2022, 23:38:51 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 13 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Tue, 12 Apr 2022, 08:36:05 EST