A systematic review of frontal lobe volume in autism spectrum disorder revealing distinct trajectories Crucitti, J, Hyde, Christian, Enticott, Peter and Stokes, Mark 2022, A systematic review of frontal lobe volume in autism spectrum disorder revealing distinct trajectories, Journal of integrative neuroscience, vol. 21, no. 2, pp. 1-10, doi: 10.31083/j.jin2102057. Attached Files Name Description MIMEType Size Downloads Title A systematic review of frontal lobe volume in autism spectrum disorder revealing distinct trajectories Author(s) Crucitti, J Hyde, Christian orcid.org/0000-0003-4833-4782 Enticott, Peter orcid.org/0000-0002-6638-951X Stokes, Mark orcid.org/0000-0001-6488-4544 Journal name Journal of integrative neuroscience Volume number 21 Issue number 2 Article ID 57 Start page 1 End page 10 Total pages 10 Publisher I M R Press Place of publication Hong Kong Publication date 2022 ISSN 0219-6352 Keyword(s) Autism spectrum disorder Development Frontal lobe volume Systematic review Summary Frontal lobe volume has been extensively researched in individuals with Autism spectrum disorder (ASD), though findings are yet to be summarised to explain the developmental trends of frontal lobe volume. The aim of the present study is to consolidate all existing frontal lobe volume and age data of autistic individuals below 30 years of age, and compare this data to non-autistic (N-ASD) controls. Following a systematic review, frontal lobe volume data were obtained from seven papers. Raw data, or the means and standard deviations of frontal lobe volume, and age, were obtained from the studies giving 372 autistic and 190 N-ASD participants. Data were plotted and analysed. Findings revealed that regression lines of fit for ASD (R2L⁢i⁢n⁢e⁢a⁢r = 0.33; R2Q⁢u⁢a⁢d⁢r⁢a⁢t⁢i⁢c = 0.52) and N-ASD (R2L⁢i⁢n⁢e⁢a⁢r = 0.14; R2Q⁢u⁢a⁢d⁢r⁢a⁢t⁢i⁢c = 0.39) were significantly different by diagnosis (linear p = 0.002, quadratic p = 0.02) with quadratic models providing significantly better fit within ASD (p < 0.001) and N-ASD (p < 0.001). Additional analyses revealed that frontal lobe volume was greater in autistic individuals than N-ASD between two and four years (F(1,31) = 12.965, p < 0.005, η2 = 0.291). In the present study, there were distinct developmental trends for frontal lobe volume between ASD and N-ASD. Language eng DOI 10.31083/j.jin2102057 Field of Research 09 Engineering 11 Medical and Health Sciences 17 Psychology and Cognitive Sciences HERDC Research category C1 Refereed article in a scholarly journal Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30166759 Document type: Journal Article Collections: Faculty of Health School of Psychology Open Access Collection Related Links Link Description Link to full-text (open access)   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Wed, 13 Apr 2022, 15:19:48 EST Wed, 13 Apr 2022, 18:28:16 EST Thu, 28 Apr 2022, 06:05:26 EST Mon, 02 May 2022, 13:31:33 EST Mon, 02 May 2022, 13:39:05 EST Mon, 02 May 2022, 15:01:51 EST Mon, 02 May 2022, 15:02:57 EST Mon, 02 May 2022, 16:59:19 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 11 Abstract Views, 2 File Downloads  -  Detailed Statistics Created: Wed, 13 Apr 2022, 15:19:48 EST