Exploring the free radical trapping ability of green tea extracts by optimizing extraction conditions Ashfaq, F, Butt, MS, Bilal, A and Suleria, Hafiz 2019, Exploring the free radical trapping ability of green tea extracts by optimizing extraction conditions, Current Bioactive Compounds, vol. 15, no. 5, pp. 540-546, doi: 10.2174/1573407214666180507120228. Title Exploring the free radical trapping ability of green tea extracts by optimizing extraction conditions Author(s) Ashfaq, F Butt, MS Bilal, A Suleria, Hafiz orcid.org/0000-0001-7045-935X Journal name Current Bioactive Compounds Volume number 15 Issue number 5 Start page 540 End page 546 Total pages 7 Publisher Bentham Science Publishers Ltd. Place of publication Beijing, China Publication date 2019 ISSN 1573-4072 1875-6646 Summary Background: The importance of polyphenols to curb lifestyle related disorders has also raised the worth of green tea polycatechins. Besides, optimization of extraction conditions is gaining wide acceptance to attain maximum polyphenols out of plant matrix. Methods: Considering the fact, in the present study, nine green tea solvent extracts were prepared by optimizing solvents; aqueous ethanol, aqueous acetone and aqueous ethyl acetate in 1:1 ratio and extraction time; 35, 50 & 65 min at constant temperature 50ºC to achieve an optimal quantity of green tea polycatechins. Results: The results indicated significant impact of extraction solvents and time on phytochemistry and free radical scavenging potential with maximum potential attained by acetone extracts of green tea at 50 min i.e. total polyphenols 1325.81±64.85 mg GAE/100g, flavonoids 139.78±5.42 mg/100g, DPPH (1,1- diphenyl-2-picrylhydrazyl) inhibition 86.69±4.01%, β-carotene & linoleic acid assay 78.47±3.57%, FRAP (Ferric Reducing Antioxidant Power) value 19.36±0.94 mM/L Fe+2, ABTS [2, 2'-azino-bis(3- ethylbenzothiazoline-6-sulphonic acid)] value 11.10±0.49 μM Trolox Eq/g and metal chelating activity 16.93±0.81 mg EDTA/g. Conclusion: Conclusively, acetone as solvent and 50 min extraction time have proven optimized extraction conditions for green tea polycatechins. Language eng DOI 10.2174/1573407214666180507120228 Field of Research 1115 Pharmacology and Pharmaceutical Sciences HERDC Research category C1.1 Refereed article in a scholarly journal Persistent URL http://hdl.handle.net/10536/DRO/DU:30171267 Document type: Journal Article Collections: Faculty of Science, Engineering and Built Environment School of Life and Environmental Sciences Related Links Link Description Connect to published version Go to link with your DU access privileges   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Tue, 31 May 2022, 08:56:33 EST Tue, 31 May 2022, 15:56:22 EST Tue, 31 May 2022, 16:09:34 EST Tue, 26 Jul 2022, 16:01:30 EST Wed, 27 Jul 2022, 16:25:23 EST Wed, 27 Jul 2022, 16:28:22 EST Wed, 27 Jul 2022, 16:46:45 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 9 Abstract Views  -  Detailed Statistics Created: Tue, 31 May 2022, 08:56:33 EST